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MYP_076626
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Basic Information
Pilosulin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C97H170N30O22
Standard
Sequence
GLGSVFGRLARILGRVIPKV
Physicochemical Analysis
2108.58 Da
12.00
3.76
3.55
0.1880
0.81
0.92
0.19
13.45
146.00
0.0500
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
839.38
-5.99
31.0
26.0
70.0
149.0
2.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0249917 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anti-Gram-negative
Staphylococcus aureus I-11574
2 μM
MIC
PMID15639237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15639237/
RECORD: Rec_0252612 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 5185
2 μM
MIC
PMID15639237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15639237/
RECORD: Rec_0253614 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus megaterium BM11
2 μM
MIC
PaperIdentification and optimization of an antimicrobial peptide from the ant venom toxin pilosulin
RECORD: Rec_0258481 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Pilosulin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperArch Biochem Biophys. 2005 Feb 15;434(2):358-64. | http://www.ncbi.nlm.nih.gov/pubmed/15639237 PMID15639237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15639237/
RECORD: Rec_0265693 VERIFIED: YES
Provenance & Taxonomy
Myrmecia pilosula [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli I-11276b
4 μM
MIC
PMID15639237 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15639237/
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