Peptide Database

Peptide NameRIPL peptide

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC89H168N40O17S

DescriptionStandard

        IPLVVPLRRRRRRRRC
    

Molecular Weight2102.61 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.53

Charge Density (pH 7.0) 0.4844

GRAVY Index-1.01

Hydrophobic Moment 0.38

Boman Index-0.88

Instability Index282.25

Aliphatic Index 109.38

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 977.44

LogP -8.83

H-bond Donors 40.0

H-bond Acceptors 26.0

Rotatable Bonds 70.0

Heavy Atoms 147.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034971 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

RECORD: Rec_0055536 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyRIPL

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0058184 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetNot available

RECORD: Rec_0110884 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0285960 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyRIPL

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other ModsRIPL peptides is conjugated to maleimide-derivatized liposomal vesicles via the thiol-maleimide reaction

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery