Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC520H815N153O147S8

DescriptionStandard

        MRTSLFLFAVFFFLAPVGSDLDAGRICGYGTARCRRNCKRQEFRVGKCPNTYPCCLKRWNVNSLNPQKDGKPKGAGLLEMAASQTSEPPFSGPSRWTVPSGTSRPVE
    

Molecular Weight11818.49 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)8.45

Net Charge (pH 7.4) 8.13

Charge Density (pH 7.0) 0.0790

GRAVY Index-0.43

Hydrophobic Moment 0.59

Boman Index-0.08

Instability Index57.29

Aliphatic Index 55.61

Aromaticity 0.1028

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4816.45

LogP -54.54

H-bond Donors 174.0

H-bond Acceptors 164.0

Rotatable Bonds 377.0

Heavy Atoms 828.0

Ring Count 23.0

Amide Bonds 114.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269676 VERIFIED: NO

Provenance & Taxonomy

OrganismCapra hircus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9925

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic