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MYP_076573
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
8 amino acids
C35H55N9O16
Standard
Sequence
ASTTTNYT
Physicochemical Analysis
857.86 Da
5.57
-0.21
-0.39
-0.0256
-0.82
0.17
-0.04
-20.65
12.50
0.1250
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
431.49
-7.85
16.0
16.0
24.0
60.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0234340 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
PaperPert C. B., Hill J. M., Ruff M. R., Berman R. M., Robey W. G., Arthur L. O., Ruscetti F. W., Farrar W. L.. Octapeptides deduced from the neuropeptide receptor-like pattern of antigen T4 in brain potently inhibit human immunodeficiency virus receptor binding and T-cells infectivity. Proc. Natl Acad. Sci. USA, 83, 9254-9258, 1986.
RECORD: Rec_0234643 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
Terminally blocked antiviral peptide
32630.0
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Bio-Activity Profile
Antiviral Anti-HIV
HIV
PaperTerminally blocked antiviral peptides Evidence URLhttps://patents.google.com/patent/US5447915A/en PatentUS 5447915 A
RECORD: Rec_0253309 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Peptide T / CCR5 entry inhibitor
32630
Structure & Mods
branched peptide architecture [Branched]
mixed L/D amino-acid peptide [Mixed]
D-Ala substitution
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Entry inhibitor CCR5 antagonist
Human immunodeficiency virus 1
PMID11530189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11530189/
RECORD: Rec_0332882 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Fusion inhibitor
Qualitative inhibition
PaperCD4 receptor binding peptides that block HIV infectivity cause human monocyte chemotaxis. Relationship to vasoactive intestinal polypeptide. PMID3026840 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/3026840/
RECORD: Rec_0353594 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]; Viral [other]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
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