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MYP_076573
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
8 amino acids
C35H55N9O16
Standard
Sequence
ASTTTNYT
Physicochemical Analysis
857.86 Da
5.57
-0.21
-0.39
-0.0256
-0.82
0.17
-0.04
-20.65
12.50
0.1250
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
431.49
-7.85
16.0
16.0
24.0
60.0
1.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0075674 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiviral
Evidence URLhttps://patents.google.com/patent/US5447915A/en PatentUS 5447915 A
RECORD: Rec_0093684 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
HIV fusion inhibitor peptide
32630
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
D-residue notation at positions 1; Mixed L/D stereochemistry with D-annotated positions 1
Bio-Activity Profile
Antiviral Anti-HIV
Radioimmunoassay , HPLC
AIDS patient plasma, in vivo; 2700 s
PMID1763193 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1763193/
RECORD: Rec_0144973 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
gp120-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Immunomodulatory
PMID11354463 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11354463/
RECORD: Rec_0197331 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Peptide T / CCR5 entry inhibitor
32630
Structure & Mods
branched peptide architecture [Branched]
mixed L/D amino-acid peptide [Mixed]
D-Ala substitution
Amidation
Bio-Activity Profile
Antiviral Anti-HIV Entry inhibitor CCR5 antagonist
HIV-1 gp120 Bal/CM235–CCR5 binding
0.00006-0.00032 μM
IC50
PMID16002156 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16002156/
RECORD: Rec_0207431 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
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