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MYP_076538
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Basic Information
Beta-defensin 123
Antimicrobial
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
67 amino acids
C370H589N99O89S8
Standard
Sequence
MKLLLLTLTVLLLLSQLTPGGTQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQPKERWWPF
Physicochemical Analysis
8104.76 Da
9.77
10.43
10.11
0.1557
-0.27
0.48
-0.07
27.87
87.16
0.1343
23950.00
24325.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3069.46
-19.26
115.0
108.0
266.0
566.0
16.0
72.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0119860 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Defensin
9598
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PaperCross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract PMID16033865 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16033865/; https://www.uniprot.org/uniprotkb/Q30KK5/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0130926 VERIFIED: NO
Provenance & Taxonomy
Pan troglodytes [Animal]
Defensin
9598
Structure & Mods
linear polypeptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A2J8PZ44/entry
RECORD: Rec_0241232 VERIFIED: NO
Provenance & Taxonomy
Pan paniscus [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ7257
RECORD: Rec_0276533 VERIFIED: NO
Provenance & Taxonomy
Gorilla gorilla gorilla [Animal]
Defensin
9595
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/A4H235/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0396552 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Beta-defensin; Defensin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Non-hemolytic
PMID11854508;15772680;12975309;11780052;15489334 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11854508/
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