Peptide Database

Peptide NameIm-1 (Non-disulfide-bridged peptide 2.6) (NDBP-2.6)

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC292H467N79O77S

DescriptionStandard

        FSFKRLKGFAKKLWNSKLARKIRTKGLKYVKNFAKDMLSEGEEAPPAAEPPVEAPQ
    

Molecular Weight6348.38 Da

Isoelectric Point (pI)10.07

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.1208

GRAVY Index-0.73

Hydrophobic Moment 0.72

Boman Index-0.15

Instability Index41.01

Aliphatic Index 64.64

Aromaticity 0.1071

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2535.78

LogP -20.14

H-bond Donors 86.0

H-bond Acceptors 85.0

Rotatable Bonds 215.0

Heavy Atoms 449.0

Ring Count 12.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400195 VERIFIED: YES

Provenance & Taxonomy

OrganismIsometrus maculatus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis NBRC 3009

Activity0.8-1.6 μM

MethodMIC

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