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MYP_076528
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Basic Information
Im-1 (Non-disulfide-bridged peptide 2.6) (NDBP-2.6)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
56 amino acids
C292H467N79O77S
Standard
Sequence
FSFKRLKGFAKKLWNSKLARKIRTKGLKYVKNFAKDMLSEGEEAPPAAEPPVEAPQ
Physicochemical Analysis
6348.38 Da
10.07
6.76
6.54
0.1208
-0.73
0.72
-0.15
41.01
64.64
0.1071
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2535.78
-20.14
86.0
85.0
215.0
449.0
12.0
58.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0316394 VERIFIED: NO
Provenance & Taxonomy
Arthropoda [Animal]
6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0318555 VERIFIED: YES
Provenance & Taxonomy
Isometrus maculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus NBRC 13276
13-25 μM
MIC
PaperA Novel Amphipathic Linear Peptide with Both Insect Toxicity and Antimicrobial Activity from the Venom of the Scorpion Isometrus maculatus.
RECORD: Rec_0328256 VERIFIED: YES
Provenance & Taxonomy
Isometrus maculatus [Animal]
NDBP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Non-hemolytic
Bacillus subtilis (Gram-positive)
PaperScorpion venom peptides with no disulfide bridges: a review PMID20139620;24184590 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20139620/
RECORD: Rec_0369990 VERIFIED: YES
Provenance & Taxonomy
Isometrus maculatus [Animal]
Im
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperBiosci Biotechnol Biochem. 2010;74(2):364-9. Epub 2010 Feb 7. | http://www.ncbi.nlm.nih.gov/pubmed/20139620 PMID20139620 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20139620/
RECORD: Rec_0373698 VERIFIED: YES
Provenance & Taxonomy
Isometrus maculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli NBRC 3972
0.4-0.8 μM
MIC
PMID20139620 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20139620/
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