Peptide Database

Peptide NameIndolicidin [K5E,R12E,R13E]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC97H116N18O20

DescriptionStandard

        ILPWEWPWWPWEE
    

Molecular Weight1854.07 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.23

Net Charge (pH 7.4) -3.44

Charge Density (pH 7.0) -0.2482

GRAVY Index-0.88

Hydrophobic Moment 0.18

Boman Index0.36

Instability Index45.73

Aliphatic Index 60.00

Aromaticity 0.3846

Extinction Coeff. Reduced 27500.00

Extinction Coeff. Oxidized 27500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 577.00

LogP 5.04

H-bond Donors 19.0

H-bond Acceptors 17.0

Rotatable Bonds 45.0

Heavy Atoms 135.0

Ring Count 13.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246259 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity100 % hemolysis at >1000 μM

MethodHemolysis

RECORD: Rec_0306425 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus ATCC 9341

Activity100 μM

MethodMIC