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MYP_076495
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Basic Information
Brevinin-2GHk (1-25)[L14A]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C118H190N32O32
Standard
Sequence
GFSSLFKAGAKYLAKQVGKAGAQQL
Physicochemical Analysis
2568.97 Da
10.18
3.76
3.54
0.1502
-0.02
0.60
0.12
11.85
78.40
0.1200
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1055.76
-10.82
36.0
36.0
89.0
182.0
3.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0149631 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
16 μM
MBC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0169672 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans NCYC 1467
16 μM
MIC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0256923 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
8 μM
MIC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0286977 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus NCTC 10788
8 μM
MIC
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
RECORD: Rec_0307294 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human microvascular endothelial cells HMEC-1
100 μM
Cytotoxicity
PMID32075067 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32075067/
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