Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length131 amino acids

Chemical FormulaC627H999N169O192S14

DescriptionStandard

        MKPISIACGVAVIIACVCVFQSAGVPLTESQVHLEEPMEETEAVQSLDQGEVSSLAREMSPEVLFRTKRQSHLSLCRYCCNCSLGLHFHNLCYVMLRMDSASLGTDESAMIDVFSLYQPAQRVLAAWAPLD
    

Molecular Weight14425.57 Da

Isoelectric Point (pI)4.93

Net Charge (pH 7.0)-7.20

Net Charge (pH 7.4) -7.76

Charge Density (pH 7.0) -0.0549

GRAVY Index0.24

Hydrophobic Moment 0.54

Boman Index0.13

Instability Index57.75

Aliphatic Index 95.27

Aromaticity 0.0611

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5719.67

LogP -56.11

H-bond Donors 204.0

H-bond Acceptors 203.0

Rotatable Bonds 472.0

Heavy Atoms 1002.0

Ring Count 19.0

Amide Bonds 139.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0372399 VERIFIED: NO

Provenance & Taxonomy

OrganismSilurus meridionalis [Animal]

FamilyHepcidin

Tax ID175797

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal