MYP_076358
polymyxin B (a mixture of polymyxin B1 to B4)
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-negative
Immunology
▸
Inflammation modulation
▸
Anti-inflammatory
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
XTXXXFLXXT
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0031609
VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
Acylation of fatty acid (6-methyloctanoic acid for polymyxin B1, 6-methylheptanoic acid for B2, octanoic acid for B3 and heptanoic acid for B4)
Cyclization
①The X in position 1, 3, 4, 5, 8 and 9 is α,γ-diaminobutyric acid (Dab). ②Dab4 links to Thr10 by amidation
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-negative
Anti-inflammatory
Providencia spp
RECORD: Rec_0034710
VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
Acylation of fatty acid (6-methyloctanoic acid for polymyxin B1, 6-methylheptanoic acid for B2, octanoic acid for B3 and heptanoic acid for B4)
Cyclization
①The X in position 1, 3, 4, 5, 8 and 9 is α,γ-diaminobutyric acid (Dab). ②Dab4 links to Thr10 by amidation
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-negative
Anti-inflammatory
other enteric bacilli
1 μg/mL
MIC50
RECORD: Rec_0042907
VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
Acylation of fatty acid (6-methyloctanoic acid for polymyxin B1, 6-methylheptanoic acid for B2, octanoic acid for B3 and heptanoic acid for B4)
Cyclization
①The X in position 1, 3, 4, 5, 8 and 9 is α,γ-diaminobutyric acid (Dab). ②Dab4 links to Thr10 by amidation
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-negative
Anti-inflammatory
Enterobacteriaceae:Citrobacter spp
RECORD: Rec_0054944
VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
Acylation of fatty acid (6-methyloctanoic acid for polymyxin B1, 6-methylheptanoic acid for B2, octanoic acid for B3 and heptanoic acid for B4)
Cyclization
①The X in position 1, 3, 4, 5, 8 and 9 is α,γ-diaminobutyric acid (Dab). ②Dab4 links to Thr10 by amidation
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-negative
Anti-inflammatory
Proteus spp
RECORD: Rec_0088900
VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]
Structure & Mods
topology not specified [Not included yet]
mixed L/D amino-acid peptide [Mixed]
Acylation of fatty acid (6-methyloctanoic acid for polymyxin B1, 6-methylheptanoic acid for B2, octanoic acid for B3 and heptanoic acid for B4)
Cyclization
①The X in position 1, 3, 4, 5, 8 and 9 is α,γ-diaminobutyric acid (Dab). ②Dab4 links to Thr10 by amidation
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-negative
Anti-inflammatory
Serratia spp
Showing 5 records on this page · Page 2 of 7