Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC428H679N119O128S15

DescriptionStandard

        MKAFSIAVAVTLVLACIYIMESSAVPFKEVQELEETGSNDTPVAAHQEMSMESWMMPNHIRQKRQSHLSLCRWCCNCCKSNTCGPCCKF
    

Molecular Weight10020.67 Da

Isoelectric Point (pI)6.79

Net Charge (pH 7.0)-0.31

Net Charge (pH 7.4) -0.83

Charge Density (pH 7.0) -0.0035

GRAVY Index-0.02

Hydrophobic Moment 0.57

Boman Index0.05

Instability Index63.95

Aliphatic Index 66.85

Aromaticity 0.0674

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3948.72

LogP -41.27

H-bond Donors 144.0

H-bond Acceptors 146.0

Rotatable Bonds 330.0

Heavy Atoms 690.0

Ring Count 15.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0339191 VERIFIED: NO

Provenance & Taxonomy

OrganismMastacembelus armatus [Bacterium]

FamilyHepcidin

Tax ID205130

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal