Peptide Database

Peptide NameTransforming growth factor beta-2

Function Ontology

Immunology ▸ Immune modulation ▸ Cytokine modulation

Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic

Standard StatusStandard

Sequence Length112 amino acids

Chemical FormulaC566H867N149O165S10

DescriptionStandard

        ALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSDTQHSRVLSLYNTINPEASASPCCVSQDLEPLTILYYIGKTPKIEQLSNMIVKSCKCS
    

Molecular Weight12719.49 Da

Isoelectric Point (pI)7.69

Net Charge (pH 7.0)0.89

Net Charge (pH 7.4) 0.43

Charge Density (pH 7.0) 0.0079

GRAVY Index-0.21

Hydrophobic Moment 0.57

Boman Index0.03

Instability Index45.13

Aliphatic Index 80.18

Aromaticity 0.1161

Extinction Coeff. Reduced 26930.00

Extinction Coeff. Oxidized 27430.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5038.18

LogP -47.62

H-bond Donors 181.0

H-bond Acceptors 178.0

Rotatable Bonds 406.0

Heavy Atoms 890.0

Ring Count 25.0

Amide Bonds 122.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365852 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyTGF-beta family

Tax ID9606; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-16; 15-78; 44-109; 48-111

Bio-Activity Profile

Function

Cytokine Growth factor TGF-beta family Growth factor signaling Angiogenic