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MYP_076225
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Basic Information
Hylin-a1 (Hy-a1; Frogs, amphibians, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiviral
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C91H157N21O20
Standard
Sequence
IFGAILPLALGALKNLIK
Physicochemical Analysis
1865.35 Da
10.00
1.76
1.55
0.0977
1.50
0.48
0.54
11.98
190.00
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
644.36
-0.79
21.0
22.0
62.0
132.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0147209 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas albopunctatus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis ATCC 19659
8 μM
MIC
PMID19056441;33742508;20560142 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19056441/
RECORD: Rec_0153610 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas albopunctatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
krusei ATCC 6258
16.7 μM
MIC
PMID19056441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19056441/
RECORD: Rec_0154618 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas albopunctatus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
32
MIC
PMID19056441;33742508;20560142 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19056441/
RECORD: Rec_0157342 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas albopunctatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
human erythrocytes
18 μM
HC50
PMID19056441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19056441/
RECORD: Rec_0171219 VERIFIED: YES
Provenance & Taxonomy
Hypsiboas albopunctatus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
64
MIC
PMID19056441;33742508;20560142 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19056441/
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