Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC369H572N94O107S12

DescriptionStandard

        MAKISFTLMFTLTLIIAAFSRTSGAMPEKPCILLLNPNYCNLSTCRMECEEQYHGTGYCVDVYPHKCVCAYSCSH
    

Molecular Weight8421.83 Da

Isoelectric Point (pI)6.78

Net Charge (pH 7.0)-0.31

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0042

GRAVY Index0.23

Hydrophobic Moment 0.44

Boman Index0.16

Instability Index32.93

Aliphatic Index 75.47

Aromaticity 0.1067

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3172.23

LogP -29.44

H-bond Donors 118.0

H-bond Acceptors 122.0

Rotatable Bonds 267.0

Heavy Atoms 582.0

Ring Count 15.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346948 VERIFIED: NO

Provenance & Taxonomy

OrganismPhaseolus angularis [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal