Peptide Database

Peptide NameBeta-defensin 105A

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC395H617N109O105S10

DescriptionStandard

        MALIRKTFYFVFAVFFILVQQPSGCQAGLEFSEPFPSGRFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRPRM
    

Molecular Weight8893.44 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0568

GRAVY Index-0.01

Hydrophobic Moment 0.46

Boman Index-0.01

Instability Index51.78

Aliphatic Index 65.00

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3441.63

LogP -30.72

H-bond Donors 127.0

H-bond Acceptors 120.0

Rotatable Bonds 293.0

Heavy Atoms 619.0

Ring Count 15.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172148 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyDefensin

Tax ID9541

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence