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MYP_076101
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Basic Information
Esculentin (1-18)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C88H155N23O22
Standard
Sequence
GIFSKLAGKKLKNLLISG
Physicochemical Analysis
1887.31 Da
10.48
3.76
3.55
0.2087
0.38
0.57
0.17
-14.14
135.56
0.0556
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
745.65
-5.55
26.0
26.0
69.0
133.0
1.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0127777 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma A549 20-30% Killing
64 μM
PMID32722535;20606068;25959536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32722535/
RECORD: Rec_0152809 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Corynebacterium jeikeium ATCC BAA-949
8 μM
MBC
PMID32722535;20606068;25959536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32722535/
RECORD: Rec_0155229 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa
8 μM
MIC
PMID32722535;20606068;25959536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32722535/
RECORD: Rec_0219250 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cytotoxic
Human keratinocytes HaCat
20 % killing at 64 μM
Cytotoxicity
PMID32722535;20606068;25959536 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32722535/
RECORD: Rec_0261262 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Esculentin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 32722535 PMID32722535 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32722535/
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