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MYP_076099
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Basic Information
CZS-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C101H168N24O25
Standard
Sequence
GFLDIVKGVGKVALGAVSKLF
Physicochemical Analysis
2118.56 Da
9.70
1.76
1.55
0.0837
1.16
0.66
0.42
-20.15
139.05
0.0952
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
780.91
-4.19
27.0
27.0
72.0
150.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0164395 VERIFIED: YES
Provenance & Taxonomy
the splendid leaf frog,Cruziohyla calcarifer,South America [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus (3.8 uM)
PMID27321580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27321580/
RECORD: Rec_0242908 VERIFIED: YES
Provenance & Taxonomy
Cruziohyla calcarifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
3.77 μM
MIC
RECORD: Rec_0256604 VERIFIED: YES
Provenance & Taxonomy
Cruziohyla calcarifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
3.77 μM
MIC
PMID27321580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27321580/
RECORD: Rec_0317355 VERIFIED: YES
Provenance & Taxonomy
the splendid leaf frog,Cruziohyla calcarifer,South America [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans (3.8 uM)
PMID27321580 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27321580/
RECORD: Rec_0336327 VERIFIED: YES
Provenance & Taxonomy
Cruziohyla calcarifer [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Amastigotes
16.72 μM
IC50
PaperPeptidomic approach identifies cruzioseptins, a new family of potent antimicrobial peptides in the splendid leaf frog, Cruziohyla calcarifer.
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