Peptide Database

Peptide NameEsculentin-2P

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC388H631N99O119S6

DescriptionStandard

        MFTTKKSMLLLFFIGTISLSFCEEERNADEEEGGEVQEEEVKRGIFSLIKGAAKVVAKGLGKEVGKFGLDLMACKVTNQC
    

Molecular Weight8779.14 Da

Isoelectric Point (pI)5.15

Net Charge (pH 7.0)-2.51

Net Charge (pH 7.4) -2.80

Charge Density (pH 7.0) -0.0313

GRAVY Index-0.01

Hydrophobic Moment 0.68

Boman Index0.06

Instability Index31.00

Aliphatic Index 86.50

Aromaticity 0.0750

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3539.30

LogP -31.60

H-bond Donors 124.0

H-bond Acceptors 123.0

Rotatable Bonds 312.0

Heavy Atoms 612.0

Ring Count 6.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0135559 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

Tax ID8409

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0348288 VERIFIED: NO