‹ ›
MYP_076025
← PREVIOUS NEXT → BACK
Basic Information
Enkephain-related peptide 2
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Standard
2 amino acids
C15H22N2O3
Standard
Sequence
FL
Physicochemical Analysis
278.35 Da
5.53
-0.24
-0.44
-0.1200
3.30
0.72
1.12
5.00
195.00
0.5000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
92.42
1.17
3.0
3.0
7.0
20.0
1.0
1.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0157888 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
1.2 pIC50
pIC50
PaperQuantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity. PMID17117396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17117396/
RECORD: Rec_0182605 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Lactoferrin-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
DPP-IV inhibitory Antidiabetic
Dipeptidyl peptidase-IV (DPP-IV)
399.58 μM
IC50
PaperDipeptidyl peptidase IV inhibitory and antioxidative properties of milk protein-derived dipeptides and hydrolysates | Nongonierma, A. et al. | DOI: 10.1016/j.peptides.2012.11.016 Evidence URLhttps://www.uniprot.org/uniprotkb/P02788/entry
RECORD: Rec_0184623 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperQuantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity PMID17117396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17117396/
RECORD: Rec_0256448 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa sauvagei [Animal]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0258071 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Model sensory peptide
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
0.67 Rcaf
Relative bitterness (Rcaf)
PaperBitterness of phenylalanine- and tyrosine-containing peptides. Agric. Biol. Chem., 51, 3309-3313, 1987
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3