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MYP_075985
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Basic Information
Hybrid peptide LFT33, LfcinB (1-15)[M10W] + Thanatin (4-21)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
33 amino acids
C189H302N62O39S4
Standard
Sequence
FKCRRWQWRWKKLGAKPVPIIYCNRRTGKCQRM
Physicochemical Analysis
4195.07 Da
11.41
10.72
10.47
0.3250
-1.05
0.59
-0.40
71.38
47.27
0.1515
17990.00
18115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1695.54
-12.08
66.0
54.0
139.0
294.0
10.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025009 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae HC2187
32 μg/mL
IC50
PMID22189867 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22189867/
RECORD: Rec_0080465 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
256 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/22189867/ PMID22189867 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22189867/
RECORD: Rec_0088285 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus ATCC 25923
16 μg/mL
IC50
Paperecombinant expression, purification, and antimicrobial activity of a novel hybrid antimicrobial peptide LFT33.
RECORD: Rec_0136323 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa ATCC 27853
32 μg/mL
IC50
PMID22189867 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22189867/
RECORD: Rec_0136855 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli O78
32 μg/mL
IC50
PMID22189867 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22189867/
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