MYP_075966
SAH-gp41 A
Antimicrobial
Antiviral
▸
Anti-HIV
▸
Antiviral
▸
Antiviral mechanism
▸
not Standard
37 amino acids
-
contains X representing unresolved or non-standard residue
XTWXEWDXEINNYTSLIHSLIEESQNQQEKNEQELLE
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0027392
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,4,8
Bio-Activity Profile
HIV-1 HxB2
RECORD: Rec_0055123
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
The 'X' at position 1 indicates Norleucine,the 'X' at position 4,8 indicates S-2-(4'-pentenyl) alanine. X(4) and X (5) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Antimicrobial
HIV-1 HxB2:inhibition of virus infection in Cf2Th-CD4-CXCR4 cells
0.0021±0.0003 μM
IC50
RECORD: Rec_0074221
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 1,4,8
Bio-Activity Profile
HIV-1 YU2
RECORD: Rec_0084146
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
The 'X' at position 1 indicates Norleucine,the 'X' at position 4,8 indicates S-2-(4'-pentenyl) alanine. X(4) and X (5) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Antimicrobial
HIV-1 YU2:inhibition of virus infection in Cf2Th-CD4-CCR5 cells
0.339±0.162 μM
IC50
RECORD: Rec_0324988
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
The 'X' at position 1 indicates Norleucine,the 'X' at position 4,8 indicates S-2-(4'-pentenyl) alanine. X(4) and X (5) are cross-linked by hydrocarbon stapling
Bio-Activity Profile
Antimicrobial
Showing 5 records on this page · Page 1 of 2