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MYP_075944
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Basic Information
Caerin 2.7
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
25 amino acids
C107H189N29O32
Standard
Sequence
GLVSSIGKALGGLLVDVVKSKGQPA
Physicochemical Analysis
2393.82 Da
9.70
1.76
1.55
0.0703
0.62
0.48
0.28
23.69
132.40
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
972.07
-10.30
33.0
34.0
82.0
168.0
1.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0246840 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]; Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
L. lactis
50 μM
MIC
PaperHost-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea.
RECORD: Rec_0270041 VERIFIED: YES
Provenance & Taxonomy
Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0339138 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]; Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P.haemolytica
>100 μg/mL
MIC
PaperHost-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea.
RECORD: Rec_0339373 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]; Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
MIC >100 ug/ml, Staphylococcus aureus ATCC 25923
>100 μg/mL
MIC
PaperHost-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea.
RECORD: Rec_0375529 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]; Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli
>100 μg/mL
MIC
PaperHost-defence peptide profiles of the skin secretions of interspecific hybrid tree frogs and their parents, female Litoria splendida and male Litoria caerulea.
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