Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC342H554N96O104S13

DescriptionStandard

        MDRSVLVAFLLLSFLLATEMGPMSAEAKTCEVESGKFKGMCMSSTNCASVCKSEPGFDGGHCQGFRRRCLCTKPC
    

Molecular Weight8091.48 Da

Isoelectric Point (pI)8.16

Net Charge (pH 7.0)1.52

Net Charge (pH 7.4) 1.12

Charge Density (pH 7.0) 0.0203

GRAVY Index0.09

Hydrophobic Moment 0.42

Boman Index0.04

Instability Index58.43

Aliphatic Index 58.53

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3186.77

LogP -36.78

H-bond Donors 120.0

H-bond Acceptors 120.0

Rotatable Bonds 271.0

Heavy Atoms 555.0

Ring Count 9.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032042 VERIFIED: NO

Provenance & Taxonomy

OrganismGossypium darwinii [Plant]

FamilyDEFL family

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal

RECORD: Rec_0078851 VERIFIED: NO

Provenance & Taxonomy

OrganismGossypium raimondii [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence