Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1151H1775N265O352S8

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFQLFIDLDLKGVVFPAGNYIDSPSVPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTTGAFNMTIAEETCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIVANTSISLNVFDQKLRGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEVVPSANAKLSKGFPLP
    

Molecular Weight25213.49 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-16.14

Net Charge (pH 7.4) -16.47

Charge Density (pH 7.0) -0.0705

GRAVY Index0.33

Hydrophobic Moment 0.54

Boman Index0.24

Instability Index45.38

Aliphatic Index 103.01

Aromaticity 0.1135

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0352170 VERIFIED: NO

Provenance & Taxonomy

OrganismLanius ludovicianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria