Peptide Database

Peptide NameNeurotoxin PRTx3-7

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC197H318N56O55S9

DescriptionStandard

        ACAGLYKKCGKGVNTCCENRPCKCDLAMGNCICKKKFVEFFGG
    

Molecular Weight4639.56 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)4.72

Net Charge (pH 7.4) 4.39

Charge Density (pH 7.0) 0.1097

GRAVY Index-0.06

Hydrophobic Moment 0.55

Boman Index-0.01

Instability Index21.49

Aliphatic Index 47.67

Aromaticity 0.0930

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1802.40

LogP -19.19

H-bond Donors 69.0

H-bond Acceptors 69.0

Rotatable Bonds 158.0

Heavy Atoms 317.0

Ring Count 5.0

Amide Bonds 45.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0382708 VERIFIED: NO

Provenance & Taxonomy

OrganismPhoneutria reidyi,Ctenus reidyi [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide2-17; 9-22; 16-33; 24-31

Bio-Activity Profile

Function

Toxin

Targethigh-voltage-activated calcium channel