Peptide Database

Peptide NameAzurocidin (Cationic antimicrobial protein CAP37) (Heparin-binding protein) (HBP) (hHBP)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Immune cell migration ▸ Chemotactic peptide

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length251 amino acids

Chemical FormulaC1167H1873N359O348S12

DescriptionStandard

        MTRLTVLALLAGLLASSRAGSSPLLDIVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDLRRRERQSRQTFSISSMSENGYDPQQNLNDLMLLQLDREANLTSSVTILPLPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRFVNVTVTPEDQCRPNNVCTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRGPDFFTRVALFRDWIDGVLNNPGPGPA
    

Molecular Weight26885.33 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)8.71

Net Charge (pH 7.4) 8.20

Charge Density (pH 7.0) 0.0347

GRAVY Index-0.12

Hydrophobic Moment 0.78

Boman Index0.02

Instability Index46.71

Aliphatic Index 82.75

Aromaticity 0.0637

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0288697 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyPeptidase S1; Elastase subfamily

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Chemotactic Cytotoxic Synergistic peptide Non-hemolytic

TargetNo Target Organism Found