Peptide Database

Peptide NameR8-RGD-lipo

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC78H144N42O17S

DescriptionStandard

        RRRRRRRRCRGDFK
    

Molecular Weight1974.31 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.53

Charge Density (pH 7.0) 0.6250

GRAVY Index-3.07

Hydrophobic Moment 0.33

Boman Index-1.66

Instability Index273.50

Aliphatic Index 0.00

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1062.04

LogP -13.52

H-bond Donors 45.0

H-bond Acceptors 27.0

Rotatable Bonds 72.0

Heavy Atoms 138.0

Ring Count 1.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0268389 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyPolyarginine

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermConjugation with cyclic RGD

Other ModsCysteine modified octa-arginine conjugated to the branch of lysine

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery