Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length485 amino acids

Chemical FormulaC2443H3893N645O686S20

DescriptionStandard

        MARDQDNTLRWATLVVLATVGTALTVTINPGFVIRISQKGLDYVCQQEIPVLQKRLENIKLPNISGSFKMKFLGNGYFSFYRMNVLNFQLPSHQIRLQPNVGLQLSISNAHVIISGKWDAKKNFFKASGDFVLRVEGISISADLKLDSNPASGRVTIACSTCSNSISKVRLHISNSKGVLGWLVRLFRKKVDSLLLKTLNKKICKILTNSVDTDLQRDIQTLPVTSKIDKVAEIDYSLVTAPITTADSLDLPLKGEFFSQAGRSPPPFDPPVMTIPPDHDRMVYLGVSDYFFNTAGLVYYQAGVLKWNLTKNMLPKRSTFHLTTDFLGQFLPQVSQEFPSMDMQLVLSTSSPPYLITQPTGLTFSPNLQAHAFAVLPNSSLASLFMLGMGMNAHMEVGANADRLTAELMMDKLHLQLIHSNVGPFPVELLQDAMNYLLPTVVLPKVNKRLQKGFPLPMPNRVQLSNLVLRSYQDFLLLGADVHLP
    

Molecular Weight53917.25 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)12.35

Net Charge (pH 7.4) 11.48

Charge Density (pH 7.0) 0.0255

GRAVY Index0.05

Hydrophobic Moment 0.75

Boman Index0.11

Instability Index39.59

Aliphatic Index 102.06

Aromaticity 0.0825

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045320 VERIFIED: NO

Provenance & Taxonomy

OrganismChinchilla lanigera (Long-tailed chinchilla) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria