Peptide Database

Peptide NameMCoTI-II

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC138H231N47O46S6

DescriptionStandard

        GGVCPKILKKCRRDSDCPGACICRGNGYCGSGSD
    

Molecular Weight3476.99 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0795

GRAVY Index-0.44

Hydrophobic Moment 0.72

Boman Index-0.15

Instability Index46.36

Aliphatic Index 45.88

Aromaticity 0.0294

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1505.71

LogP -22.38

H-bond Donors 59.0

H-bond Acceptors 55.0

Rotatable Bonds 115.0

Heavy Atoms 237.0

Ring Count 3.0

Amide Bonds 34.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0411985 VERIFIED: YES

Provenance & Taxonomy

OrganismMomordica cochinchinensis [Animal]

Structure & Mods

Configcyclic/stapled peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetU-937/GTB

MethodIC50

FIRST PREV 1 2 3 4

Showing 1 records on this page Ã‚Â· Page 4 of 4