Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC477H782N124O131S8

DescriptionStandard

        MKLFLVLIILLFEVSKGAARPRKCFGNIKGYCRKKCRMGEIYEIACTNGKLCCVNEEENKAYQEVAKPPQPSTKPDLKLDYVILPTVTVNTIPL
    

Molecular Weight10606.58 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)5.45

Net Charge (pH 7.4) 5.11

Charge Density (pH 7.0) 0.0580

GRAVY Index-0.06

Hydrophobic Moment 0.56

Boman Index0.02

Instability Index33.84

Aliphatic Index 97.45

Aromaticity 0.0745

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4101.77

LogP -31.46

H-bond Donors 144.0

H-bond Acceptors 145.0

Rotatable Bonds 355.0

Heavy Atoms 740.0

Ring Count 14.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010654 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence