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MYP_075697
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Basic Information
L5K5W8
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C71H127N17O12
Standard
Sequence
LLKKLLKWLKK
Physicochemical Analysis
1410.87 Da
10.60
4.76
4.54
0.4323
-0.13
0.81
-0.13
-10.56
177.27
0.0909
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
500.21
1.85
18.0
17.0
53.0
100.0
2.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0260813 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Human red blood cells
128 μg/mL
Hemolysis
PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
RECORD: Rec_0266183 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Salmonella typhimurium ATCC 14028
4 μg/mL
MIC
PaperStructural characterization of de novo designed L5K5W model peptide isomers with potent antimicrobial and varied hemolytic activities. Molecules. 2013 Jan 11;18(1):859-876. doi: 10.3390/molecules18010859. PMID: 23344198. PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
RECORD: Rec_0284481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
4 μg/mL
MIC
PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
RECORD: Rec_0288604 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermis ATCC 12228
4 μg/mL
MIC
PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
RECORD: Rec_0297701 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Hemolytic
Human erythrocytes
128 μg/mL
MHC
Paperhttps://pubmed.ncbi.nlm.nih.gov/23344198/ PMID23344198 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23344198/
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