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MYP_075677
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Basic Information
Colicin-E7 (EC 3.1.-.-)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibiotic activity
Enzyme / Catalytic activity ▸ Hydrolase
Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
575 amino acids
C2664H4244N804O842S8
Standard
Sequence
MSGGDGRDHNSGAHNTGGNINGGPTGLGGNGGASDGSGWSSENNPWGGGSGSGVHWGGGSGHGNGGGNGNSGGGSNSSVAAVAFGFPALAAPGAGTLGIAVSGEALSAAIADIFAALKGPFKFSAWGIALYGILPSEIAKDDPKMMSKIVTSLPAETVTNVQVSTLPLDQATVSVTKRVTDVVKDTRQHIAVVAGVPMSVPVVNAKPTRTPGVFHASFPGVPSLTVSTVKGLPVSTNLPRGITEDKGRTAVPAGFTFGGGSHEAVIRFPKESGQKPIYVSVTDVLTPAQVKQRQDEENRLQQEWNDTHPVEVAERNYEQARAELDQANKDVARNQERQAKAVQVYNSRKSELDAANKTLADAKAEIKQFERFAREPMAAGHRMWQMAGLKAQRAQTDVNNKKAAFDAAAKDKSDADAALGAALERRKQKENKEKDSKDKLDKESKRNKPGKATGKGKPVGDKWLDDAGKDSGAPIPDRIADKLRDKEFKSFDDFRKKFWEEVSKDPELSKQFKDSNKTNIQKGKAPFARKKDQVGGRERFELHHDKPISQDGGVYDMDNIRVTTPKRHIDIHRGK
Physicochemical Analysis
61263.60 Da
9.40
13.70
12.66
0.0238
-0.71
0.86
-0.11
35.23
62.83
0.0574
51450.00
51450.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0131000 VERIFIED: NO
Provenance & Taxonomy
Shigella sonnei [Bacterium]
Colicin/Pyocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease
Escherichia coli
Evidence URLhttps://www.uniprot.org/uniprotkb/A0A8B4CJR0/entry
RECORD: Rec_0157135 VERIFIED: NO
Provenance & Taxonomy
Escherichia coli [Bacterium]
Colicin/Pyocin
562
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic Non-ribosomal
Escherichia coli
Qualitative functional evidence
PMID31652858 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31652858/; https://www.uniprot.org/uniprotkb/Q8GN45/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0282855 VERIFIED: NO
Provenance & Taxonomy
Salmonella enterica [Bacterium]
Colicin/Pyocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease
Escherichia coli
PaperSKESA: strategic k-mer extension for scrupulous assemblies PMID30286803 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30286803/