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MYP_075637
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Basic Information
Juruin
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
38 amino acids
C172H280N48O50S6
Standard
Sequence
FTCAISCDIKVNGKPCKGSGEKKCSGGWSCKFNVCVKV
Physicochemical Analysis
4012.74 Da
9.08
4.70
4.39
0.1236
-0.04
0.32
0.02
14.64
53.68
0.0789
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1591.09
-19.13
61.0
61.0
136.0
276.0
5.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004811 VERIFIED: YES
Provenance & Taxonomy
Toe spider [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antifungal
Candida albicans
2-2.5 μM
MIC
PaperJuruin: an antifungal peptide from the venom of the Amazonian Pink Toe spider, Avicularia juruensis, which contains the inhibitory cystine knot motif
RECORD: Rec_0036446 VERIFIED: YES
Provenance & Taxonomy
Avicularia juruensis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans MDM8
2.5-5 μg/mL
MIC
PMID22973266 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22973266/
RECORD: Rec_0047974 VERIFIED: YES
Provenance & Taxonomy
Avicularia juruensis [other]
Neurotoxin 12 (Hwtx-2); 03 (juruin) subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Toxin Hemolytic
PMID22973266 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22973266/
RECORD: Rec_0058211 VERIFIED: YES
Provenance & Taxonomy
Avicularia juruensis [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
3-24, 7-30, 16-35.
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicand
2 μM
MIC
RECORD: Rec_0061723 VERIFIED: YES
Provenance & Taxonomy
Avicularia juruensis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida krusei IOC 4559
2.5-5 μg/mL
MIC
PMID22973266 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22973266/
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