Peptide Database

Peptide NameSyn-larvacin-94

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC135H231N41O33

DescriptionStandard

        AGKETIRQFLKKKIQEKGKIAKRAW
    

Molecular Weight2956.53 Da

Isoelectric Point (pI)10.73

Net Charge (pH 7.0)6.79

Net Charge (pH 7.4) 6.59

Charge Density (pH 7.0) 0.2718

GRAVY Index-1.09

Hydrophobic Moment 0.69

Boman Index-0.35

Instability Index14.66

Aliphatic Index 74.40

Aromaticity 0.0800

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1264.46

LogP -9.42

H-bond Donors 45.0

H-bond Acceptors 40.0

Rotatable Bonds 110.0

Heavy Atoms 209.0

Ring Count 3.0

Amide Bonds 26.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003870 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity18.23 μM

MethodIC50

RECORD: Rec_0254833 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity<20 μM

MethodCC50