Peptide Database

Peptide NameNeuropeptide K

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antifungal

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity

Neurological / Signaling ▸ Tachykinin peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC174H281N51O53S

DescriptionStandard

        DADSSVEKQVALLKALYGHGQISHKRHKTDSFVGLM
    

Molecular Weight3967.47 Da

Isoelectric Point (pI)8.40

Net Charge (pH 7.0)1.02

Net Charge (pH 7.4) 0.66

Charge Density (pH 7.0) 0.0284

GRAVY Index-0.41

Hydrophobic Moment 0.35

Boman Index-0.04

Instability Index45.49

Aliphatic Index 86.67

Aromaticity 0.0556

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1690.60

LogP -17.69

H-bond Donors 59.0

H-bond Acceptors 58.0

Rotatable Bonds 137.0

Heavy Atoms 279.0

Ring Count 5.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0227423 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyNeuropeptide K

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibacterial Antifungal Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Growth regulation Development regulation Receptor modulation Immunomodulatory

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0254817 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyTachykinin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Tachykinin Neuropeptide Neuromodulator

RECORD: Rec_0422284 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication