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MYP_075606
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Basic Information
Brevinin CTcu4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C125H197N27O25S2
Standard
Sequence
FLPFIAGMAAKFLPKIFCAISKK
Physicochemical Analysis
2542.20 Da
10.04
3.75
3.52
0.1629
1.04
0.60
0.39
36.36
102.17
0.1739
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
810.25
-0.82
28.0
31.0
82.0
179.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0087086 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit erythrocytes (55% Hemolysis at 200 microg/ml
200 μg/mL
Hemolysis
PMID24161537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
RECORD: Rec_0109989 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli MG1655
20 μg/mL
MIC
PMID24161537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
RECORD: Rec_0157582 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent WO 2019/077634 A2 Evidence URLhttps://patents.google.com/patent/WO2019077634A2/en PatentWO 2019/077634 A2
RECORD: Rec_0212944 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
25 μM
MIC
RECORD: Rec_0219008 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus coagulans ATCC 7050
PMID24161537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
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