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MYP_075606
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Basic Information
Brevinin CTcu4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
23 amino acids
C125H197N27O25S2
Standard
Sequence
FLPFIAGMAAKFLPKIFCAISKK
Physicochemical Analysis
2542.20 Da
10.04
3.75
3.52
0.1629
1.04
0.60
0.39
36.36
102.17
0.1739
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
810.25
-0.82
28.0
31.0
82.0
179.0
6.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017305 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus MTCC 9542
25 μg/mL
MIC
PMID24161537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
RECORD: Rec_0042442 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Vibrio cholerae
25 μg/mL
MIC
PMID24161537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
RECORD: Rec_0044050 VERIFIED: YES
Provenance & Taxonomy
Clinotarsus curtipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
20 μM
MIC
RECORD: Rec_0051262 VERIFIED: YES
Provenance & Taxonomy
Lithobates berlandieri [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0059913 VERIFIED: YES
Provenance & Taxonomy
Indian bicoloured [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24161537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24161537/
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