Peptide Database

Peptide NameKiller protein of pyocin s3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length555 amino acids

Chemical FormulaC2718H4268N762O820S20

DescriptionStandard

        MAIGYFLLVGDKTTCGGQIITGDHTMTFNGKATAREGDKVTCGKHPGTYTIVGGVSDVFDMGRKLAGTLDSVSTCPCRARFINSEMDSYEKQEQPNHQATAPVNMAVQNFSSPVKEASNVQPEPLVTKAPPIPVFAKSCLRGKGCTDAGTEAEPADNFGRMAIYQVPSSPAPVTPQKPEPPPQGKQHPPEPDKPQDKKLPWYKRWFRDGEDKAEAAAAAVAATARSAVAEGEGLVMRYIGGGAISAGRWLAAPNPVTIGLMGLFYSPKLNDGEEDYLTPYRLRQIAEQYGKASTRVRFRWIRDEKSGRITVQGYHVSPEGGLDKVSVRMMTLNRTTGNYEFWEPGENRPTILWTPNEQEFKVPAHTGNEEQPFIPSQITVLPIPDKVGSDIESLPMPEEKDFRDYILVLPIPNMPPVYVYLSKPPVKLFEVDLYRNFAGRLRNGTHADHMPSAAAVKARLKALYPKLLPSELNSDSKNVSAIIIPEEVHQKLSQTYGGRNSSEQIERDSQDLRAALDRNFDAIKPSLKRYGATEVQLENARQRMHKINEEQGLYK
    

Molecular Weight61380.88 Da

Isoelectric Point (pI)7.61

Net Charge (pH 7.0)1.40

Net Charge (pH 7.4) 0.42

Charge Density (pH 7.0) 0.0025

GRAVY Index-0.57

Hydrophobic Moment 0.75

Boman Index-0.06

Instability Index48.73

Aliphatic Index 70.32

Aromaticity 0.0775

Extinction Coeff. Reduced 62800.00

Extinction Coeff. Oxidized 63175.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155646 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus luminescens subsp. mexicana [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperPhotorhabdus khanii subsp. guanajuatensis subsp. nov., isolated from Heterorhabditis atacamensis, and Photorhabdus luminescens subsp. mexicana subsp. nov., isolated from Heterorhabditis mexicana entomopathogenic nematodes PMID30688647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30688647/