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MYP_075541
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Basic Information
vif 93-107
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Vif multimerization inhibitor
Standard
15 amino acids
C75H120N20O27
Standard
Sequence
RYSTQVDPDLADQLI
Physicochemical Analysis
1733.87 Da
4.05
-2.24
-2.44
-0.1492
-0.55
0.41
-0.11
-26.45
104.00
0.0667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
782.60
-7.95
26.0
25.0
55.0
122.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0024237 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Replication inhibition
HIV-1
Mammalian: 1 h; Yeast: 2 min; E. coli: 2 min
PaperPotent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. | Yang B, Gao L, Li L, Lu Z, Fan X, Patel CA, Pomerantz RJ, DuBois GC, Zhang H. | J Biol Chem. 2003 Feb 21;278(8):6596-602. | DOI:10.1074/jbc.M210164200 | PMID:12480936 PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0099312 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0199108 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:inhibit vif-vif binding
PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0334329 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Vif multimerization inhibitor
H9
25 %
Inhibition
PaperPotent suppression of viral infectivity by the peptides that inhibit multimerization of human immunodeficiency virus type 1 (HIV-1) Vif proteins. PMID12480936 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12480936/
RECORD: Rec_0422802 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/