Peptide Database

Peptide NameBeta-defensin 2 (Fragment)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC169H265N55O40S7

DescriptionStandard

        PRREMFLCRGGSCHFGGCPIHLIKVGRCFGFRSCC
    

Molecular Weight3931.71 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)5.08

Net Charge (pH 7.4) 4.83

Charge Density (pH 7.0) 0.1450

GRAVY Index0.15

Hydrophobic Moment 0.46

Boman Index0.00

Instability Index67.84

Aliphatic Index 52.86

Aromaticity 0.1143

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1500.58

LogP -15.03

H-bond Donors 62.0

H-bond Acceptors 54.0

Rotatable Bonds 127.0

Heavy Atoms 271.0

Ring Count 8.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051661 VERIFIED: NO

Provenance & Taxonomy

OrganismTaeniopygia guttata [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0383126 VERIFIED: YES

Provenance & Taxonomy

OrganismTaeniopygia guttata [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)