Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length445 amino acids

Chemical FormulaC2272H3531N549O631S18

DescriptionStandard

        MLPFLILLLPCTNHAFGLNPAIKAVLANKGLKYGTHIGTDWMHEKILSMKVPDVTGGVYIGFGTVKYVLDGISVSSCDVPEPSVNFSEGSGLKIVINGLSIAVRVMVIFGLIGASFLFNLDLTLLVDIGSDDKGHMSILSKYCSARINSATINFHGGASWIFQPFVDCFKSRIKALIEEKICPLVDQHVADLEQYLTELQVSFQIDPIVVLDVPLTNAPLISSSSLGLDLKGEFYSIKSPKEPPFEAKAFDLPKDDGFMLSLGLSEFSFNSASYAYFDTGHLHITVTDEMIPPTSPLRLNTSYFGPFIPQLPKLFPNMLMLLEVYAREIPMFSFLPGEVTLDFPGAVKALAILPNRTLTPLFKLNADSLFSGKVYISEGKLKGLMELKNFTLTLASSEIGTFQVGYENAANDIQWLTLWVSSFKSRETKCWNQSLFCRLRLWKKV
    

Molecular Weight49209.81 Da

Isoelectric Point (pI)5.94

Net Charge (pH 7.0)-4.83

Net Charge (pH 7.4) -5.66

Charge Density (pH 7.0) -0.0109

GRAVY Index0.26

Hydrophobic Moment 0.60

Boman Index0.21

Instability Index32.94

Aliphatic Index 104.04

Aromaticity 0.1101

Extinction Coeff. Reduced 50880.00

Extinction Coeff. Oxidized 51255.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0398084 VERIFIED: NO

Provenance & Taxonomy

OrganismEsox lucius [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria