Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC327H519N95O87S12

DescriptionStandard

        FVCLWALRMICVCVCVSVRTDTARGSFIAELDHCHTNGGYCVRAICPPSARRPGSCFPEKVPCCKYMK
    

Molecular Weight7557.98 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)4.84

Net Charge (pH 7.4) 4.38

Charge Density (pH 7.0) 0.0712

GRAVY Index0.29

Hydrophobic Moment 0.55

Boman Index0.06

Instability Index45.60

Aliphatic Index 71.62

Aromaticity 0.0882

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2866.04

LogP -27.38

H-bond Donors 112.0

H-bond Acceptors 106.0

Rotatable Bonds 236.0

Heavy Atoms 521.0

Ring Count 14.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0083483 VERIFIED: NO

Provenance & Taxonomy

OrganismMus spicilegus [Animal]

FamilyDefensin

Tax ID10103

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal