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MYP_075379
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Basic Information
Defensin MT5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
38 amino acids
C196H304N64O47S7
Standard
Sequence
GFFCPYNGYCDRHCRKKLRRRGGYCGGRWKLTCICIMN
Physicochemical Analysis
4533.37 Da
9.69
7.78
7.43
0.2048
-0.60
0.70
-0.22
64.62
41.05
0.1579
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1829.56
-17.26
74.0
63.0
148.0
314.0
9.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0128358 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
15 μM
MIC
RECORD: Rec_0192350 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Fusarium graminearum 8/1
4 μM
IC50
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0248198 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Listeria fleischmannii DSM 24998
15 μM
MIC
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0252914 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Listeria welshimeri DSM 20650
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0287304 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Plasmodium falciparum[90-100% Inhibition = 50 microM]
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
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