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MYP_075379
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Basic Information
Defensin MT5
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
38 amino acids
C196H304N64O47S7
Standard
Sequence
GFFCPYNGYCDRHCRKKLRRRGGYCGGRWKLTCICIMN
Physicochemical Analysis
4533.37 Da
9.69
7.78
7.43
0.2048
-0.60
0.70
-0.22
64.62
41.05
0.1579
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1829.56
-17.26
74.0
63.0
148.0
314.0
9.0
39.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011221 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Listeria grayi DSM 20601
8 μM
MIC
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0051404 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Escherichia coli D31
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0082239 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Plasmodium falciparum[70-80% Inhibition = 25 microM]
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0091944 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Listeria monocytogenes DSM 20600
1 μM
MIC
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
RECORD: Rec_0102996 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Listeria seeligeri DSM 20751
15 μM
MIC
PMID26255244;27822206 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26255244/
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