Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC516H854N144O143S9

DescriptionStandard

        MRLLLMLAILLFHKSTVTEQLKKCWGEYIRGHCRKICKITEIRQVLCENGRYCCLNILELEARKKITKPTRPKPMTYAITLPQDEDINVDNFLSPKANST
    

Molecular Weight11651.76 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)6.63

Net Charge (pH 7.4) 6.19

Charge Density (pH 7.0) 0.0663

GRAVY Index-0.26

Hydrophobic Moment 0.75

Boman Index-0.07

Instability Index34.62

Aliphatic Index 98.50

Aromaticity 0.0600

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4667.86

LogP -38.49

H-bond Donors 168.0

H-bond Acceptors 161.0

Rotatable Bonds 397.0

Heavy Atoms 812.0

Ring Count 14.0

Amide Bonds 107.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049399 VERIFIED: NO

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence