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MYP_075354
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Basic Information
Gramicidin S-10
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FPXXXFPXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211160 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
16.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0233099 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
64.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0235598 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
32.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0237088 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
8.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0252000 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Hemolytic
human red blood cells
100 % hemolysis at 500 μM
Hemolysis
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
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