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MYP_075354
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Basic Information
Gramicidin S-10
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
10 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
FPXXXFPXXX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0121392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 12228
64.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0130023 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
Ornithine, tBuGly= tert-butylglycine, tBuAla=tert-butylalanine
Bio-Activity Profile
Antimicrobial
Human erythrocytes
9.3±1.07 μM
HC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/20848624/ PMID20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20848624/
RECORD: Rec_0135773 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus cereus ATCC 11778
4.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0148276 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
8.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
RECORD: Rec_0159230 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bacteriocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
unspecified non-canonical residue at 3,4,5,8,9,10
Bio-Activity Profile
Antimicrobial Antibacterial
Proteus mirabilis 1190901236
64.0 μg/mL
MIC
PMID20951594;20848624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20951594/
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