Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC102H156N28O32S4

DescriptionStandard

        GIVEQCCHKPCSIFDLQNYCN
    

Molecular Weight2414.76 Da

Isoelectric Point (pI)5.32

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.51

Charge Density (pH 7.0) -0.0567

GRAVY Index-0.11

Hydrophobic Moment 0.40

Boman Index0.05

Instability Index48.04

Aliphatic Index 69.52

Aromaticity 0.0952

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 978.65

LogP -10.36

H-bond Donors 35.0

H-bond Acceptors 36.0

Rotatable Bonds 77.0

Heavy Atoms 166.0

Ring Count 4.0

Amide Bonds 24.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0322045 VERIFIED: YES

Provenance & Taxonomy

OrganismPiaractus mesopotamicus [Animal]

FamilyInsulin

Tax ID42528

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0358981 VERIFIED: YES